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KMID : 1130620180140030387
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Journal of Clinical Neurology
2018 Volume.14 No. 3 p.387 ~ p.392
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Clinical Application of 2017 McDonald Diagnostic Criteria for Multiple Sclerosis
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Mantero Vittorio
Abate Lucia
Balgera Roberto
La Mantia Loredana
Salmaggi Andrea
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Abstract
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Background and Purpose: McDonald criteria for multiple sclerosis diagnosis have been revised over the years, diagnostic procedures have been simplified and earlier diagnosis facilitated. The new 2017 revision introduces other important changes, with a further simplification for the diagnosis. Oligoclonal bands reassume a more relevant role in the workup.
Methods: We describe 3 typical cases of patients admitted for clinically isolated syndrome and illustrate how the application of the new criteria can change the diagnostic approach with respect to the previous criteria.
Results: In two of the three cases a diagnosis of multiple sclerosis is now possible.
Conclusions: The new 2017 Multiple Sclerosis criteria may have an important impact in clinical practice with an earlier treatment to avoid the risk of disease dissemination. Their application requires a careful assessment to avoid misdiagnosis and mistreatments.
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KEYWORD
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multiple sclerosis, clinically isolated syndrome, criteria, McDonald criteria, oligoclonal bands
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